![]() These include venlafaxine, a serotonin-noradrenaline reuptake inhibitor (SNRI) antidepressant, and tricyclic antidepressants such as clomipramine, imipramine, and desipramine. Other medications that may help control symptoms belong to specific classes of antidepressants. This medication should not be used in conjunction with alcohol or any other central nervous system (CNS) depressant due to the risk of respiratory depression and other significant CNS depressant effects. Possible adverse effects are dizziness, headache, and nausea. Sodium oxybate is effective in reducing both the frequency and intensity of attacks. Food and Drug Administration (FDA) for the treatment of cataplexy. Sodium oxybate at doses between 6 and 9 grams (g) nightly is the medication approved by the U.S.
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